Efficacy of Nitroglycerine Spray on cardiovascular response during laryngoscopy and intubation.

Dr. Surendra Kumar; Dr. Ratan Kumar Choudhary; Dr. Desh Pal Singh; Dr Amit Kumar; Dr Atul Kaushik

Volume : IX, Issue : XI, November - 2019

Efficacy of Nitroglycerine Spray on cardiovascular response during laryngoscopy and intubation.

Dr. Surendra Kumar, Dr. Ratan Kumar Choudhary, Dr. Desh Pal Singh, Dr Amit Kumar, Dr Atul Kaushik

Abstract :

Laryngoscopy during intubation is associated with significant increase in pulse rate and blood pressure. The present prospective randomized comparative study conducted at Rama Medical College Hospital and Research Centre, Pilkhuwa, Hapur aimed to assess the efficacy of Nitroglycerine spray 2 puffs (0.8mg) for attenuation of such hemodynamic stress response in patients undergoing laryngoscopy and intubation for general anaesthesia for major operation who were compared to patients receiving premedication only. The study found that the use of Nitroglycerine spray(0.8%) administered intranasal 2 minutes before induction is associated with statistically significant blunting of the hypertensive effect but not the tachycardia response of the cardiovascular system to laryngoscopy and intubation while under G.A