Volume : X, Issue : V, May - 2020

Efficacy of Tacrolimus in subepithelial infiltrate secondary to adenoviral keratoconjunctivitis.

Bivas Bala, Sima Biswas

Abstract :

Purpose: The aim of this study was to work out the efficacy and safety of tacrolimus (0.03%) ointment for the treatment of subepithelial corneal infiltrates (SEIs) secondary to adenoviral keratoconjunctivitis. Methods: This study is about patients of post adenoviral sub epithelial infiltrate who were treated with tacrolimus 0.03% eye ointment twice daily. We are assed the length of treatment, best corrected visual acuity before and after treatment, IOP changes, symptom score and SEI before and after treatment. Results: Sixty–two eyes of Thirty–eight patients were included. Of them twenty–four (63.1%) had bilateral involvement. All of them were treated with 0.03% tacrolimus eye ointment. The average length of treatment was 117 days, and the mean follow–up duration was 183 days. After 4 months continuous treatment patients were improved (p<0.001%) in term of visual acuity, improved symptomatic score and reduced SEI score. No significant adverse effect noted except mild burning sensation in five (13.1%) patients. Conclusions: Topical tacrolimus ointment is an effective option for treatment of subepithelial infiltrate associated with adenoviral keratoconjunctivitis.

Keywords :

Article: Download PDF    DOI : 10.36106/ijar  

Cite This Article:

EFFICACY OF TACROLIMUS IN SUBEPITHELIAL INFILTRATE SECONDARY TO ADENOVIRAL KERATOCONJUNCTIVITIS., BIVAS BALA, SIMA BISWAS INDIAN JOURNAL OF APPLIED RESEARCH : Volume-10 | Issue-5 | May-2020

Number of Downloads : 152

References :