Emerging azithromycin resistance in organisms causing Enteric fever in Uttarakhand.

Anchal Kumar Tripathi; Swati U; Balramji Omar; Nowneet Kumar Bhat

Volume : X, Issue : V, May - 2020

Emerging azithromycin resistance in organisms causing Enteric fever in Uttarakhand.

Anchal Kumar Tripathi, Swati U, Balramji Omar, Nowneet Kumar Bhat

Abstract :

Enteric fever is associated with significant morbidity worldwide. More than 26 million culture positive cases of enteric fever are seen throughout the world. This disease is endemic in India. Emergence of fluoroquinolone resistant and multidrug resistant strains has changed the global landscape of typhoid. There has been gradual shift in minimum inhibitory concentration effective antibiotics. Emergence of resistance to third generation cephalosporins and macrolides in India and neighboring countries poses a new challenge. Multi–drug resistant typhoid has been reposted from various parts of India. But studies involving pediatric age group are rare from Uttarakhand. This study was planned to study the resistance pattern of enteric fever from this region. Out of 67 cases included in the study, 20 were culture positive. 1 isolate each was resistant to ceftriaxone and cefixime while 3 isolates were resistant to azithromycin