EVALUATION OF GASTROPROTECTIVE ACTIVITY OF YASTIMADHU CHURNA IN PYLORUS LIGATED GASTRIC ULCER IN WISTAR ALBINO RATS

Dr. Ashanka Bhardwaj; Dr. Pooja Gupta; Dr. Sukrant Sharma; Dr. Sarabjeet Kour

Volume : IX, Issue : VIII, August - 2019

EVALUATION OF GASTROPROTECTIVE ACTIVITY OF YASTIMADHU CHURNA IN PYLORUS LIGATED GASTRIC ULCER IN WISTAR ALBINO RATS

Dr. Ashanka Bhardwaj, Dr. Pooja Gupta, Dr. Sukrant Sharma, Dr. Sarabjeet Kour

Abstract :

Peptic ulcer is a common disease which is caused due to eak in the barriers of gastric mucosa against the acid erosions with pain as a chief symptom. Peptic ulcers can be corelated to parinaam and annadrava shoola. Yastimadhu has Sothanashaka,Vranaropana, Pittajit and wound healing properties. Therefore it may be effective in treatment of peptic ulcers. Preventive activity of the yashtimadhu in the peptic ulcers was studied on experimental albino rats. Ulcers were introduced by shay’s method of pyloric ligation. Ulcer index, gastric contents for acidity, ph, protein and carbohydrate contents and peptic activities were checked. In the end of the study it showed less tissue damage in histopathological examination as compared to control group. The cytoprotective action of the yashtimadhu helps in the healing of the ulcer. Thus aqueous extract of yashtimadhu choorna proves to be a promising drug in the management of peptic ulcers.