GROWTH PROFILE OF CHILDREN WITH THALASSEMIA MAJOR

Dr Rahul Jahagirdar; Dr Shalin Parikh; Dr Ruma Deshpande; Dr Sanjay Lalwani

Volume : VII, Issue : I, January - 2017

GROWTH PROFILE OF CHILDREN WITH THALASSEMIA MAJOR

Dr Rahul Jahagirdar, Dr Shalin Parikh, Dr Ruma Deshpande, Dr Sanjay Lalwani

Abstract :

Beta Thalassemia, the commonest form of thalassemia is associated with retarded growth, delayed development of secondary sexual characteristics and abnormal physical features. The present study longitudinally evaluated the auxological and pubertal status in 27 diagnosed children of Beta Thalassemia major in respect to their haemoglobin levels, Bio–chemical parameters, Endocrine functions and skeletal maturation.

Results –

Mean pre–transfusion blood haemoglobin levels were 7.28gm% and 10.49 gm % (Pre and Post transfusion). The children were significantly stunted and wasted. The mean serum ferritin level was 3591 ng/dl and 4293 ng/dl at 1^st and 3^rd visit, respectively. The degree of stunting and wasting was directly proportional to the values of serum ferritin. Liver function tests were derailed. Calcium levels were low. Thyroid function tests , blood sugar levels and onset of puberty was not delayed .Regular long term follow–up for evolving endocrine abnormalities will be needed.