Volume : III, Issue : X, October - 2013

Impact of Alkaloids Fraction from Jatropha Curcas on Monocytes

Revathi. M, Ravi. D

Abstract :

Jatropha curcas is a tropical and subtropical plant. It has a wide distribution habitat.The ethanolic extract of the Jatropha curcas was extracted and their phytochemical and antioxidant assays were performed. Using that ethanolic extract of Jatropha curcas (EEJC) the alkaloids were isolated and their invitro activity was investigated by culturing the monocytes and their viability was assessed. RNA was isolated from the alkaloid treated monocytic cells and were processed to RT–PCR for amplification, whereas Cycloxygenase (COX ) and Lipoxygenase (LOX) assays were carried out by the same alkaloid treated cultured cells. The results were compared and it will conclude that the plant extract having the capacity to reduce the COX and LOX assay activity. Therefore, the Jatropha curcas having a potent bioactive principle compounds treated against the monocytes. In future these active principle compounds of Jatropha curcas can be assayed for curing different human aliments on pathogenic diseases

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Article: Download PDF   DOI : 10.36106/ijar  

Cite This Article:

Revathi.M, Ravi. D / Impact of Alkaloids Fraction from Jatropha Curcas on Monocytes / Indian Journal of Applied Research, Vol.3, Issue.10 October 2013


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