Phytochemical Analysis and Inhibitiory Activity of Petroleum Ether Extract of T. Divaricata Leaves Against Carbohydrate Hydrolysing Enzyme Α–Amylase

Sagar M. Rothe; Dr. Zia H. Khan; Rahul L. Meshram

Volume : IV, Issue : IX, September - 2014

Phytochemical Analysis and Inhibitiory Activity of Petroleum Ether Extract of T. Divaricata Leaves Against Carbohydrate Hydrolysing Enzyme Α–Amylase

Sagar M. Rothe, Dr. Zia H. Khan, Rahul L. Meshram

Abstract :

T.divaricata a common garden plant in tropical countries has been used as a traditional medicine. Phytochemical analysis of T.divaricata revealed the presence of Steroids, Reducing Sugar, Proteins, Terpenoids, Gums, Tannins, and Saponins. In this study significant inhibition effect of carbohydrate hydrolysing enzyme alpha amylase in the leaves extract of T. divaricata have been observed. As result the concentration of carbohydrate i.e. glucose will be controlled and in turns it will controlling type 2 Diabetes mellitus. So, further comprehensive pharmacological and phytochemical investigations are needed to elucidate the specific chemical compounds responsible for alpha amylase inhibition and their mode of actions. It can be further purified and used as an alternative for synthetic drugs.