Volume : X, Issue : V, May - 2020

SEROLOGICAL PROFILE OF HEPATITIS B VACCINATED PERSONS WITH SPECIAL REFERENCE TO QUANTITATION OF ANTI-HBs ANTIBODIES TITERS

Dr. Sireesha Chava

Abstract :

BACKGROUND:Hepatitis B Virus infection is a serious global health problem with risk of contracting HBV by health care workers is four– times greater than that of general adult population. High risk groups such as health care workers should be vaccinated and receive a booster vaccination if their anti–HBs Antibodies levels decrease below 10mIU/ml. OBJECTIVES: My objectives of this study was to evaluate the efficacy of vaccine by determining the antibody titres in various Groups of hepatitis b vaccinated persons. METHODS:. Blood samples from 100 Health Care Workers were tested for HBsAg, anti–HBe, anti–HBc and anti–HBs antibodies by ELISA method. RESULTS: anti–HBsAg antibodies titers in vaccinated health care workers, 84/90 (93.3%) developed protective levels of antibodies. It was observed that females( 97%) have a higher prevalence of anti–HBsAg antibodies than males(85%). According to duration elapsed since vaccination it was observed that higher titers are seen in vaccinated individuals of <5years Duration(97.3%) and amount of titers decreased after 10yrs of vaccination (76.90%). CONCLUSION:These studies show that complete vaccine administration must be taken and that the ability to respond is influenced by several factors including genetic factors, age, sex etc

Keywords :

Article: Download PDF    DOI : 10.36106/ijar  

Cite This Article:

SEROLOGICAL PROFILE OF HEPATITIS B VACCINATED PERSONS WITH SPECIAL REFERENCE TO QUANTITATION OF ANTI-HBS ANTIBODIES TITERS, Dr. Sireesha Chava INDIAN JOURNAL OF APPLIED RESEARCH : Volume-10 | Issue-5 | May-2020


Number of Downloads : 230


References :