Studies on in–vitro Anti Microbial Potential of Rhizospheric Soil Bacteria against Multi Drug Resistant Clinical Isolates

Manish Dhore; Dipali Barate; M. Musaddiq

Volume : III, Issue : VII, July - 2014

Studies on in–vitro Anti Microbial Potential of Rhizospheric Soil Bacteria against Multi Drug Resistant Clinical Isolates

Manish Dhore, Dipali Barate, M. Musaddiq

Abstract :

Antimicrobial resistance provides a survival benefit to microbes and makes it harder to eliminate infections from the body. In the present investigation we tried to find a new antimicrobial agent producing bacteria from rhizosphere soil. In this view study has been performed to find out some excellent rhizospheric soil bacteria which are active against multi drug resistant clinical pathogens. In the present study P. aeruginosa , S. aureus, E. coli, K. pneumoniae were isolated from different clinical samples. All the isolates were then subject to antibiotic susceptibility testing by disc diffusion method. Susceptibility testing by disc diffusion method. Out of 86 isolates 62.79 % isolates were found to be multi drug resistant (MDR). The rhizospheric isolates S2 (Bacillus spp) & S5 (P.fluorescens) were found to exert good antimicrobial activity against 8 most resistant clinical isolates. Because of huge emergence of multidrug resistant (MDR) bacteria reported in our study and previously reported studies it is an urgent need to discover new therapeutics that would be effective against MDR strain. Rhizosphere soil gives an excellent option as a source for search of some new alternative medicines.