Volume : IV, Issue : III, March - 2014

STUDY OF TSH LEVELS IN SUBJECTS WITH AND WITHOUT METABOLIC SYNDROME

Cariappa Kb, Venkatesh G

Abstract :

 Background: Metabolic syndrome (MetS) refers to a cluster of features conferring the risk for cardiovascular disease and type 2 diabetes mellitus. Considering the fact that the thyroid dysfunction is also associated with the risk for CVD, this study was undertaken to estimate the levels of thyrotropin stimulating hormone (TSH) in subjects with and without metabolic syndrome. Materials and Methods: The study population included 50 subjects with metabolic syndrome and 50 subjects without metabolic syndrome. Blood pressure and anthropometric measurements were measured in all the study subjects, following which a fasting blood sample was obtained for the estimation of fasting blood sugar (FBS), lipid profile and TSH. The data obtained was analyzed using SPSS software. AHA/NHLBI definition was used to define MetS. The values obtained were compared using student t test and correlated using Pearson correlation. Results: TSH levels were high among the subjects with MetS and it was statistically highly significant (<0.01). Pearson‘s product–moment correlation of TSH with age and the components of the MetS yielded a positive and highly significant (<0.01) correlation with age, FBS and waist circumference (WC). It also significantly correlated with triglyceride (TGL) (<0.05). The prevalence of hypothyroidism in MetS was 46% and the hyperthyroidism was 6%. Conclusion: High TSH was found to be associated with metabolic syndrome, suggesting that hypothyroid subjects are prone for cardiometaboilc risk

Keywords :

Article: Download PDF   DOI : 10.36106/ijar  

Cite This Article:

Dr. Cariappa KB, Dr. Venkatesh G. “STUDY OF TSH LEVELS IN SUBJECTS WITH AND WITHOUT METABOLIC SYNDROME” Indian Journal of Applied Research, Vol.IV, Issue. III

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