Synthesis, Structural Elucidation and Anti Microbial Screening of N–(4–aryl amine)–2–{[4–phenyl–5–(pyridin–4–yl)–4H–1,2,4–triazol&n

Mahyavanshi Jyotindra B; Parmar Kokila A.; Mahato Anil K.

Volume : IV, Issue : I, January - 2014

Synthesis, Structural Elucidation and Anti Microbial Screening of N–(4–aryl amine)–2–{[4–phenyl–5–(pyridin–4–yl)–4H–1,2,4–triazol&n

Mahyavanshi Jyotindra B, Parmar Kokila A. , Mahato Anil K.

Abstract :

A new series of 2-[4-phenyl-5-(pyridine-4-phenyl)-4H-[1,2,4]triazole-3ylSulfanyl]-N-aryl-acetamide have been synthesized by the condensation of 4-phenyl-5-(pyridine-4-yl)-4H-1,2,4-triazole-3-thiol and 2-Chloro-N-(aryl)-acetamide in presence of anhydrous potassium Carbonate. The Structure of Synthesized compound was assigned by H¹NMR,MASS Spectra,IR Spectra and Elemental Analysis .All the compound were Screened for their in-vitro Antibacterial, Antifungal and anti tuberculosis activity.