stability is the most important requirement of complete denture prosthesis therapy owing to its contribution to physiologic comfort to the denture wearer. Perioral musculature plays an important role in stability of complete denture and in a patient with advanced residual ridge resorption it becomes a critical factor for long term success. Neutral zone concept utilizes the physiologic functional activity of perioral musculature to mold the external polished surface of denture which enhances the stability with respect to dentofacial kinetics. The present case report describes rehabilitation of severely resorbed mandibular ridge by complete denture prosthesis with neutral zone concept and conventional maxillary complete denture prosthesis.