Basti (Medicated enema) is one of the five therapeutic procedures in Panchakarma, is frequently used in the management of different Vatavyadhi (neurological disorders). It is a herbo – mineral preparation prepared by systematic step wise procedure described in Ayurvedic classics. The most important materials used in the preparation of Basti are Makshika (Honey), Saindava (Rock salt), Sneha (Fatty material), Kalka (Paste of herbs), Kwatha (Decoction of herbs). It is a unique preparation as well as widely practiced all over among the treatment modalities of panchakarma. Therefore, here is an attempt is made to understand the rationality and importance behind the specific order of mixing of Basti ingredients during the process of mixing of it and also identifying the practical difficulties faced during the mixing of Basti dravya’s in the order mentioned and solutions for them on the modal Erandamooladi Niruha Basti