A Clinico Pathological study of Non Melanotic Skin cancers (NMSC)

Dr. Manilal. B; Dr.Narendra H; Dr. Bhargavi. D; Dr.N.Rukmangada

Volume : IX, Issue : IV, April - 2020

A Clinico Pathological study of Non Melanotic Skin cancers (NMSC)

Dr. Manilal. B, Dr. Narendra H, Dr. Bhargavi. D, Dr. N. Rukmangada

Abstract :

Background: To describe the demographic and pathologic characteristics of NMSCs. Methods: This retrospective study was done from 2012 to 2018. Patients with biopsy proven SCC and BCC were included. Detailed history, physical examination and tumor characteristics and treatment details were recorded and analyzed. Results: Among 70 patients 27 (38.6%) patients were female and 43(61.4%) patients were male. Majority of patients were in the age group of more than 60 years. Forty two (60 %) patients had SCC, 28 (40 %) patients had BCC. Fifty seven patients were treated with wide local excision. Amputation was done in 13 SCC patients. Head was the most common site followed by lower limb. There was a significant association between the type of cancer and the involved site (P–value was <0.001). Head was the most common site involved in BCC and extremities were most common site affected in SCC. Regional lymph nodes were involved in 5 patients with SCC and 1 patient with BCC at initial presentation. Among 42 SCC patients, 14 (5.8%) patients had recurrence. Regional nodal and distant recurrences were noted in 12 and 2 patients respectively. Two SCC patients with distant metastasis received palliative chemotherapy with taxane and platinum compounds. Conclusion: NMSCs are more prevalent in sixth and later decades. Major contributory risk factor includes intermittent rather than constant UV exposure. Head and neck is the most common site of involvement. Surgical resection remains the most common treatment method for NMSCs.