A STUDY OF EPIDEMIOLOGY AND CLINICAL PROFILE OF ACUTE PANCREATITIS IN A TERTIARY HOSPITAL IN SOUTH INDIA

Dr.SASHIDHAR REDDY B; Dr. DR.N.RAJESH

Volume : IV, Issue : XII, December - 2015

A STUDY OF EPIDEMIOLOGY AND CLINICAL PROFILE OF ACUTE PANCREATITIS IN A TERTIARY HOSPITAL IN SOUTH INDIA

Dr. Sashidhar Reddy B, Dr. Dr. N. Rajesh

Abstract :

AIMS AND OBJECTIVES: To study the clinical presentation of acute pancreatitis in a tertiary hospital in South India. METHODS: This prospective study was conducted in a tertiary hospital between June 2011 to January 2013. All the patients who were diagnosed to have acute pancreatitis by clinical examination, laboratory, radiological and biochemical investigations were considered as cases. On admission after history and examination, patients were stratified according to Ranson’s criteria. On discharge or death patients were classified according to Atlanta classification. Prediction of severity was compared among the two classifications. RESULTS: Total 90 patients were diagnosed to have acute pancreatitis. Majority of the patients were in the age group 30 – 40 years and male to female ratio was 3:1. In our study the commonest etiology was alcohol (53.3%) followed by gall stones (21.1%). Majority presented with abdominal pain( 92%) followed by vomiting(77%) and jaundice(14%). Serum lipase is more sensitive than serum amylase for the diagnosis of acute pancreatitis. Computed Tomography (CT) of abdomen was 100% sensitive for the diagnosis. Median hospital stay was 5 days. 66% were managed in the ward while 34% required ICU care. The overall mortality rate was 6%. CONCLUSION: The incidence of acute pancreatitis was found to be higher in younger age group. Serum amylase and lipase both were (80 % sensitivity) used for diagnosis where ever possible. Timely intervention by endoscopist and surgeons are crucial to reduce morbidity and mortality