A STUDY OF LIVER DYSFUNCTION DETERMINANTS IN NORMAL AND TYPE 2 DIABETIC SUBJECTS IN INDIAN POPULATION

Dr.Mamta Choudhary; Dr.R.K.Vyas

Volume : IV, Issue : II, February - 2015

A STUDY OF LIVER DYSFUNCTION DETERMINANTS IN NORMAL AND TYPE 2 DIABETIC SUBJECTS IN INDIAN POPULATION

Dr. Mamta Choudhary, Dr. R. K. Vyas

Abstract :

The association of abnormal liver function tests are not uncommon encounter in diabetes mellitus patients. Previous data on evaluation of liver function tests in patients with type 2 diabetes mellitus showed considerable debates, so this study was conducted to evaluate the liver function test abnormalities in patients with type 2 DM in India. It is a case control comparative study included biochemically and clinically confirmed 50 cases of Type 2 DM (age ranges 12-60Years) and results are compared with 50 age and sex matched healthy controls. LFTs were performed using standard methods. Our study shows that serum AST,ALT,ALP,GGT and bilirubin significantly increase and total protein was significantly decrease in type 2 DM patients when compared to control subjects.Thus the emerging evidence suggests the abnormal LFTs may be marker for diagnosis and prognosis of diabetes mellitus.