A STUDY ON PREVALANCE OF METABOLIC SYNDROME IN POLYCYSTIC OVARIAN SYNDROME AND ITS PHENOTYPES

Dr. Bishnu Prasad Das; Dr. Alakananda; Dr. Ishaa Goel

Volume : VI, Issue : XI, November - 2017

A STUDY ON PREVALANCE OF METABOLIC SYNDROME IN POLYCYSTIC OVARIAN SYNDROME AND ITS PHENOTYPES

Dr. Bishnu Prasad Das, Dr. Alakananda, Dr. Ishaa Goel

Abstract :

Background: Polycystic Ovarian Syndrome (PCOS) is a common gynaecological endocrinopathy characterized by chronic anovulation and hyperandrogenism. The disorder is heterogeneous and is one of the most common treatable causes of infertility. PCOS is characterized by insulin resistance with compensatory hyperinsulinemia. Insulin resistance also plays a role in the metabolic syndrome (MBS). Limited information is available pertaining to the prevalence of MBS in Indian PCOS women.

OBJECTIVE: To study prevalence of MBS patients with PCOS in Indian women and its phenotypes.

Materials and Methods: Present study is a hospital based cross‑sectional study carried out over a period of 12 months in department of Obstetrics and Gynaecology, Gauhati Medical College And Hospital, Guwahati, Assam , India. Total of 66 newly diagnosed case of PCOS as per Rotterdam Criteria(2003) were taken. MBS was defined according to American Heart Association /National Heart Lung Blood Institute AHA/NHLBI(ATP III 2005) definition.

Results and Observations: In the present study metabolic syndrome was found to be present in 36.37% of the study group. Of the 4 phenotypes of PCOS the classic type was most commonly associated with MBS and P+H type had least association with MBS seen in 62.5% and 4.17% respectively

Conclusions: PCOS women have high frequency of MBS. MBS are not only associated with the complete PCOs but also in other varieties of PCOS more so in obese than lean PCOS. So all PCOS patients need screening for all these problems when being evaluated in clinical practice.