Adenocarcinoma of Gall Bladder: A Papillary Variant

Dr. Deesha N. Bhemat; Dr. D.B.Borkar; Dr. Reeta Dhar; Dr. Shilpi Sahu

Volume : V, Issue : XII, December - 2016

Adenocarcinoma of Gall Bladder: A Papillary Variant

Dr. Deesha N. Bhemat, Dr. D. B. Borkar, Dr. Reeta Dhar, Dr. Shilpi Sahu

Abstract :

Adenocarcinomas account for 90% of gallbladder carcinomas out of only 25% is papillary adenocarcinoma. Gallstones cause chronic irritation and inflammation of the gallbladder, which leads to mucosal dysplasia and subsequent carcinoma. We report a case of 40 year old male who came to the surgery OPD with chief complaints of pain in abdomen and USG was suggestive of cholelithiasis due to which cholecystectomy was being performed. Grossly, the resected gallbladder was 7x3 cm in size and Microscopically tissue comprising of varying sizes of papillae lined by tumor cells showing stratification, marked nuclear pleomorphism, increased N:C ratio with prominent nucleoli was seen in the sections studied. Papillary gallbladder adenocarcinoma is a distinct clinical entity that represents about 5% of all malignant gallbladder tumors. It is not so common but has the best prognosis of the histological types.