Assessment of thyroid hormonal status among Hyperglycemic Pregnant Women at Tertiary level of Health care System of Haryana, INDIA

Dr. Ragini Sing Ghalaut; Dr. Veena Sing Ghalaut; Dr. Rajju Tiwari; Indra Prasad Adhikari; Dr. Madhumita Sarkar; Dr. Ritika Sethi

Volume : V, Issue : XI, November - 2016

Assessment of thyroid hormonal status among Hyperglycemic Pregnant Women at Tertiary level of Health care System of Haryana, INDIA

Dr. Ragini Sing Ghalaut, Dr. Veena Sing Ghalaut, Dr. Rajju Tiwari, Indra Prasad Adhikari, Dr. Madhumita Sarkar, Dr. Ritika Sethi

Abstract :

Introduction:Gestational diabetes mellitus (GDM) and thyroid disease are the most common endocrine abnormalities during pregnancy. GDM is defined as any degree of glucose intolerance with onset or first recognition during pregnancy. Diabetes complication and abnormal thyroid profile during pregnancy is associated with adverse maternal and foetal outcome. Therefore this study was designed to find out thyroid hormonal status in hyperglycemic pregnant women. Objective: To find out thyroid hormonal status among hyperglycaemic pregnant women attending OPD/IPD. Material and methods: 20 pregnant women having increased blood glucose (GDM and Diabetic pregnant women) were included in test group and 20 gestational age matched females with normal blood glucose were taken as control. Plasma glucose was estimated by enzymatic method by autoanalyzer. Serum free thyroxine, free tri–iodothyronine, and thyroid stimulating hormone were assessed in each subjects by chemiluminescence technique. Results: In the present study thyroid disorder in patients of GDM and DM have found no significant association (p>0.05) with control group. However subclinical hypothyroidism is more prevalent thyroid dysfunction in the three groups. Conclusion: This study showed that Subclinical hypothyroidism is more prevalent thyroid dysfunction in hyperglycemic pregnant women, so that It is suggested to screen the thyroid profile in patients of GDM and DM