Volume : IX, Issue : V, May - 2020

Comparison of prevalence of subclinical hypothyroidism in urban and rural population of Northern India

Sunil Kumar, R C Gupta

Abstract :

Introduction: Subclinical hypothyroidism (SCH) is defined as high serum TSH concentration with normal Free Thyroxine (FT4) and Free Triiodothyronine (FT3) concentrations, associated with few or no signs and symptoms of hypothyroidism.It is reported to have a prevalence of 4–10% in general population and 7–26% in geriatric population. There are very few reports on prevalence of subclinical hypothyroidism in the general population of India, especially rural population. Material and Methods: This cross–sectional study was conducted on 400 subjects from rural areas (areas under Gram Panchayat) and 400 subjects from urban areas (areas under Municipal Corporation or Municipal Committee) in Amber Tehsil of Jaipur District. Serum specimens of all the subjects were analyzed for FT3, FT4 and TSH by chemiluminescence. Prevalence of SCH in urban and rural areas was compared by Chi square test. P<0.05 was taken as significant. Results: Serum TSH was found to be above normal in 9.75% (N=39) of the urban subjects and 10.75% (N=43) of the rural subjects. The concentration of serum FT3 and FT4 was normal in all the urban and rural subjects. The difference in prevalence of subclinical hypothyroidism in urban and rural areas was not significant. The proportion of subjects having high TSH was more in women than in men in urban as well as rural populations but the difference was not significant. Conclusion: The prevalence of subclinical hypothyroidism was9.75% in urban and 10.75% in rural population of Northern India. The difference in urban and rural prevalence was not significant.

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Article: Download PDF    DOI : 10.36106/ijsr  

Cite This Article:

COMPARISON OF PREVALENCE OF SUBCLINICAL HYPOTHYROIDISM IN URBAN AND RURAL POPULATION OF NORTHERN INDIA, Sunil Kumar, R C Gupta INTERNATIONAL JOURNAL OF SCIENTIFIC RESEARCH : Volume-9 | Issue-5 | May-2020


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