Volume : IX, Issue : I, January - 2020

EFFECT OF SELENIUM SUPPLIMENTATION IN BRONCHIAL ASTHMA IN CHILDREN IN THE AGEGROUP OF 1-12 YEARS

Prashant Patil, Pushparaj Patil

Abstract :

DESIGN: RANDOMISED CONTROLLED TRIAL SETTINGS: TERTIARY CARE HOSPITAL METHOD– PATIENTS: Children of age group between 1–12 years attending OPD/IPD with symptoms of asthma, having recurrent wheeze (more than 2 episodes in 1 year) were included in study. INTERVENTION: Patients were randomized in 2 groups i.e. cases and controls. One group (cases) has received Selenium supplementation according to RDA for respective age of patient for duration of 6 month along with their ongoing management for asthma. Second group (controls) received Placebo for duration of 6 month along with their ongoing management for asthma. MAIN OUTCOME MEASURE(S): History of symptoms and treatment was documented in every 15 days interval. Anthropometric measurements were recorded in every 3 month interval up to 6 months. RESULTS: It was observed that there was significant improvement in grade of asthma in 9 (21.4%) patients of Se group as compared to 2 (4.8%) patients in control group(p value=<0.05). There was significant reduction in number of wheezing episodes in Se group. 22(52.38%) patients in Se group had less than 5 episodes in 6 month period as compared to 8(19.05%) in control group. The difference in number of hospitalizations required in Se group was significantly less(p=<0.05) as compared to control group. There after 6 month follow up which is Statistically significant improvement in grade of PEM was seen in Se group as compared to control group(p value <0.05). OBJECTIVE: Primary objective was to Study Effect of selenium supplementation in onchial asthma in children of age group 1–12 years. Secondary objective was to study the effect of selenium supplementation on growth in asthmatic children. CONCLUSIONS:– Selenium supplementation as per RDA is beneficial in improving symptomatology of asthma, nutritional status and hence quality of life of asthmatic patients in pediatric age group.

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Article: Download PDF    DOI : 10.36106/ijsr  

Cite This Article:

EFFECT OF SELENIUM SUPPLIMENTATION IN BRONCHIAL ASTHMA IN CHILDREN IN THE AGEGROUP OF 1-12 YEARS, PRASHANT PATIL, PUSHPARAJ PATIL INTERNATIONAL JOURNAL OF SCIENTIFIC RESEARCH : Volume-9 | Issue-1 | January-2020

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