Epidural analgesia for labour and delivery : Double blind comparison of fentanyl and bupivacaine with sufentanil and bupivacaine

Dr. Gosai Jigarkumar; Dr. Doctor Tarlika

Volume : IV, Issue : XII, December - 2015

Epidural analgesia for labour and delivery : Double blind comparison of fentanyl and bupivacaine with sufentanil and bupivacaine

Dr. Gosai Jigarkumar, Dr. Doctor Tarlika

Abstract :

INTRODUCTION The most popular method to control labour pain is epidural administration of opioids with local anesthetic agent .We have selected widely accepted option of epidural administration of Inj. Sufentanil 10�g and Inj. Fentanyl 100�g with 0.125% Inj. Bupivacaine for the labour pain. AIMS AND OBJECTIVES We compared the efficacy of epidural inj Bupivacaine with inj fentanyl and Bupivacaine with sufentanil with respect to their onset of action ,effectiveness , duration of analgesia & side effects of the drugs in mother and baby. METHODS AND MATERIALS Total fifty females of age group 18–30yrs, full term, primi or multigravida with vertex presentation, belonging to physical status ASA grade I or II were selected for randomised double blind study with local ethical committee approval. When patient had pain or VAS score >3, group F received 0.125% Bupivacaine + fentanyl100�g while group S received 0.125% Bupivacaine + sufentanil10�g as 10ml bolus dose through epidural route. All patients details were noted in preformed proforma with prior informed consent & Statistical analysis was done with student t test. OBSERVATION AND RESULTS Duration of analgesia was significantly(p=0.035) prolonged in group S (338+/–177.4 min) as compared to group F (248.2+/–133.8 min) . In new born APGAR score noted at 1 min and 5 min were statistically significant (p=0.0006 &p=0.03 respectively). CONCLUSION We conclude that epidural administration of sufentanil with bupivacaine provides better analgesia.