Evaluation of Calcitonin Gene Related  Peptide and Parathyroid Hormone  Related Peptide Levels in Normotensive,  Mild and Severe Preeclampsia.

SONALI YADAV; URMILA SINGH; MADHU MATI GOEL; SHANKAR MADHAV NATU; YOGENDRA SINGH YADAV

Volume : III, Issue : I, January - 2014

Evaluation of Calcitonin Gene Related Peptide and Parathyroid Hormone Related Peptide Levels in Normotensive, Mild and Severe Preeclampsia.

Sonali Yadav, Urmila Singh, Madhu Mati Goel, Shankar Madhav Natu, Yogendra Singh Yadav

Abstract :

The objective of the study was to determine whether serum circulating peptides, calcitonin gene related peptide and parathyroid hormone related peptide differ between normotensive women and women developing mild and severe preeclampsia. A case-control study of 132 women with preeclampsia (mild = 117; severe = 15) and 132 matched women with normotensive pregnancy. Samples were collected at the time of diagnosis. CGRP and PTHrP levels were highest in normotensive followed by mild preeclampsia and severe preeclampsia. Mean calcitonin gene related peptide (CGRP) and parathyroid hormone related peptide (PTHrP) levels show inverse relation with severity of Preeclampsia.