Evaluation of serum level of Trace elements at day 5 and 10 after enrollment and its association with severity of Head injury in trauma patients

Mohammad Rashid; Rajesh Kumar Suman

Volume : IV, Issue : VI, June - 2015

Evaluation of serum level of Trace elements at day 5 and 10 after enrollment and its association with severity of Head injury in trauma patients

Mohammad Rashid, Rajesh Kumar Suman

Abstract :

Introduction: Head injury is a recognized as a major public health problem that is a frequent cause of death and disability in young people and makes considerable demands on health services. Alteration of the trace elements such as Zinc and copper has great importance in head injury patients. Objective: To evaluates serum level of Copper, Magnesium, Zinc and Chromium in trauma patients at day 5 and 10 after the enrollment and its association with head injury. Methods: Special designed performa was used to collect data of Trauma patients. The data were expressed in percentage. Results: The Total of 34 head injury patients were enrolled in the study. Majority of patients (41.2%) in present Study were aged between 21–30 years. Majority of patients (67.6%) were males. On day 5, only 2.9 % of patients had GCS scores between 12 to 15 which is corresponds with the mild category of head injury. Majority of patients had GCS Scores <8 which corresponds with the severe category of head injury. 41.2% patients had GCS Scores between 8 to 11 which corresponded with the moderate category of head injury.At Day 5, the mean serum copper level were 0.066 mg/dl, mean Zinc, magnesium and chromium levels were 0.224,0.643mg/dl and 0.249 ug/ml respect.Mean level of all the trace elements were found to be lower in moderate group as compared to severe group, however, the difference between two group was found to be statistically significant for copper and zinc levels.On day 10, Mean serum copper, Zinc, magnesium and chromium were found to be 0.093, 0.302, 1.439 mg/dl and 0.27 ug/ml respectively.At day 10, Mean copper levels were found to be minimum among patients who had day 10 GCS scores in severe category (0.034mg/dl). Mean copper levels were found to be maximum among patients who had day 5 GCS scores in mild category (0.126 mg/dl). Conclusion:. The Present study conclude that, at day 10, copper and zinc showed a significant association with the status severity of head injury however. magnesium was not significant.