Volume : III, Issue : XII, December - 2014

Hypolipidemic Activity of Bryonia Scabrella (Linn) Leaves in Mice Fed With High Fat Diet

S. Velvizhi, M. Vijipriya

Abstract :

Hyperlipidemia has been ranked as one of the greatest risk factors contributing to prevalence and severity of coronary heart diseases. It is characterized by elevated level of triglycerides (TG), cholesterol, low-density lipoprotein (LDL), very low -density lipoprotein (VLDL) and decreased high-density lipoprotein (HDL) in the blood. The present study was aimed to evaluate the hypolipidemic activity of the aqueous extract of Bryonia scaella (Linn) leaves. Hyperlipidemia was induced by mice fed with high fat diet. The mice fed with high fat diet for 30 days (one month) exhibited significant(p<0.001) increase in TC, TG, LDL-C and VLDL and decrease in HDL-C as compared to normal diet control. Treatment with aqueous extract of Bryonia scaella (100mg/kg body weight) showed significant decrease in elevated TC, TG, LDL-C, and VLDL, with significant increase in HDL-C as compared to high cholesterol diet control. Based on these investigations, it was concluded that the leaves of Bryonia scaella (Linn) leaves posses marked anti hyperlipidemic activity

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Article: Download PDF   DOI : 10.36106/ijsr  

Cite This Article:

S. VELVIZHI,M.VIJIPRIYA Hypolipidemic Activity of Bryonia Scabrella (Linn) Leaves in Mice Fed With High Fat Diet International Journal of Scientific Research, Vol : 3, Issue : 12 December 2014

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