Volume : IX, Issue : II, February - 2020

Immunophenotyping of Blasts in Chronic Myelogenous Leukemia with Blast Crisis – Experience of Tertiary Care Centre

Biren Parikh, Beena Brahmbhatt, Arshi Tandon, Kalaharaghini R. , Birva Brahmbhatt

Abstract :

Immunophenophenotyping plays a major role in characterization of blasts in Chronic myeloid leukemia– Blast crisis (CML–BC). This study evaluated total 52 cases of CML–Blast crisis in which thirty–two (61.5%) cases were of myeloblastic crisis and twenty (38.5) cases of lymphoblastic crisis. Predominant myeloid markers were CD33 (97%), cd13 (94%), CD117 (75%) and MPO (59%). Predominant lymphoid markers were CD19 (100%), CD79a (95%) and CD10 (80%). This differentiation has a very important role in patient management and outcome.

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Article: Download PDF    DOI : 10.36106/ijsr  

Cite This Article:

IMMUNOPHENOTYPING OF BLASTS IN CHRONIC MYELOGENOUS LEUKEMIA WITH BLAST CRISIS‾EXPERIENCE OF TERTIARY CARE CENTRE, Biren Parikh, Beena Brahmbhatt, Arshi Tandon, Kalaharaghini R., Birva Brahmbhatt INTERNATIONAL JOURNAL OF SCIENTIFIC RESEARCH : Volume-9 | Issue-2 | February-2020


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