Volume : II, Issue : VII, July - 2013

Mast cells in Surgically Resected Appendices

Dr Alpa A Shah, Dr Moxda Patel, R Jitendra, Dr Deepak Joshi

Abstract :

In the present study total 100 appendices were studied by using simple histochemical techniques, an attempt was made to study the mast cell in variety of appendicular pathology to find out the mast cell variation in the normal and inflamed appendix. Appendices were received from 97 patients operated for the signs and symptoms of appendicitis. 3 normal appendices were collected. After morphological assessment, appendices were grouped in to acute appendicitis (64), recurrent (28), worm infestation (1), tuberculosis (1), appendix from tuberculosis affecting ileocaecal region (1) , appendix from typhoid perforation of intestine (1), appendix from mucin secreting adenocarcinoma of colon (1). Recurrent or subacute appendicitis, mast cell count is intermediate between normal appendices and acute appendicitis. This indicates that mild inflammation causes degranulation of less number of mast cells or due to simultaneous reparative process in recurrent appendicitis, mast cell number are increasing from low count in acute appendicitis towards normal count in normal appendices. As mucosal mast cell count is more liable to changes with inflammation or fiotic process as demonstrated by lower mucosal mast cell count as compared to submucosal mast cell count in acute inflammation and higher mucosal mast cell count than submucosal in different grades of fiosis, it can be concluded that initial stimulus may be luminal.

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Article: Download PDF   DOI : 10.36106/ijsr  

Cite This Article:

DR ALPA A SHAH, DR MOXDA PATEL, R JITENDRA, DR DEEPAK JOSHI Mast cells in Surgically Resected Appendices International Journal of Scientific Research, Vol : 2, Issue : 7 July 2013

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