Prevalence of High Level Aminoglycoside  Resistance of Enterococci in Various  Clinical Specimens From A Tertiary Care  Hospital of North Delhi.

Swati Chaudhary; Swastika Aggarwal; Pawan Kumar; SK Aggarwal; FC Garg

Volume : III, Issue : III, March - 2014

Prevalence of High Level Aminoglycoside Resistance of Enterococci in Various Clinical Specimens From A Tertiary Care Hospital of North Delhi.

Swati Chaudhary, Swastika Aggarwal, Pawan Kumar, Sk Aggarwal, Fc Garg

Abstract :

Enterococcus is the opportunistic pathogens, exhibits intrinsic resistance to a number of antimicrobial agents in addition to acquired multidrug resistance. The present study was conducted to determine enterococci exhibiting high–level aminoglycoside resistance in a tertiary care hospital. Enterococci were isolated from various clinical specimens and identified to the species level. High–level resistance (HLR) to gentamicin and streptomycin was determined by the clinical ATB ENTROC 5 strip, semi– automated system mini API method. Beta–lactamase production was detected using chromogenic method. Out of 60 enterococci isolates, 73.3% were found to have HLR to both streptomycin and gentamicin in which HLR to streptomycin was most common (95%). None of them produced beta–lactamase. Therefore, there is an urgent need for more minimal and restricted use of antimicrobials in to minimize the spread of such strains.