PREVALENCE OF VITAMIN D DEFICIENCY AND TO EVALUATE THE EFFICACY OF VITAMIN D GRANULES 60,000 IU SUPPLEMENTATION IN VITAMIN D DEFICIENT APPARENTLY HEALTHY ADULTS IN URBAN AREAS

Dr Sanjeev Kumar; Dr Seema Rani; Taruna; Dr Garima Bhutani

Volume : VII, Issue : VI, June - 2018

PREVALENCE OF VITAMIN D DEFICIENCY AND TO EVALUATE THE EFFICACY OF VITAMIN D GRANULES 60,000 IU SUPPLEMENTATION IN VITAMIN D DEFICIENT APPARENTLY HEALTHY ADULTS IN URBAN AREAS

Dr Sanjeev Kumar, Dr Seema Rani, Taruna, Dr Garima Bhutani

Abstract :

Healthy adults were screened for 25(OH)D by Enzyme linked immunoassaymethod. Those found to be deficient or insufficient in vitamin D (defined as 25(OH)D <30 ng/ml) were supplemented with oral vitamin D₃ granules 60,000 IU/week for eight weeks. Serum 25(OH)D level was estimated at the end of 8 weeks. Results: Atotal of 100 subjects (age 20–50 years) were enrolled for the study. Baseline data and follow up data was available for 90 subjects whoconsumed a total of eight sachets as per the study protocol. Of these 90 subjects, 91% subjects were found to be vitaminD deficient (<20 ng/ml) , 8.89% were vitamin D insufficientand 0.11% were vitamin D sufficient. The mean plasma vitamin D 25(OH)D level was 12.43 ng/ml (�4.29) at baseline. At the end of thestudy, the mean 25(OH)D plasma level was noted to be 46.34 ng/ml (�13.57). The mean change from baseline was 23.91 ng/ml(�13.25). Conclusion: This study showed that vitamin D deficiency ishighly prevalent in the urban healthy adult population. Eight weeks of vitamin D3 60,000 IU/week oral granules supplementationincreased serum 25(OH) D to optimal levels.