Volume : VI, Issue : XII, December - 2017

Role of Extrinsic muscle involvement in tongue cancer: worse or not– A review

Dr Akhlak Hussain, Dr Nida Siddiquee

Abstract :

 AJCC 8th edition recently exclude the extrinsic muscle invasion (EMI) from the T staging including depth as the only criteria up to T3 stage. We review the prognostic and predictive role of EMI and found it to be an important tool for prediction of lymph node metastasis and hence, it is an important prognostic feature.

           

Introduction

It seems to be controversial excluding the EMI from the AJCC 8th edition. Proponents suggest them to be the superficial muscles and their effect on prognosis can be nullified by including depth of invasion instead. Opponents argue that there is a major difference regarding the prognosis in the tumor with or without EMI. We review systemically including most of the publications on this issue.< clear="all" />  

Discussion

           Regional metastasis to cervical lymph nodes results in  50% decrease in 5–year survival in patients with nodal disease.1,2 Thus these represents the most significant prognostic factor in HNSCC. Lymph node status is an issue of paramount importance in the treatment of HNSCC, especially in resectable cases. The management of clinically or radiologically positive node is elective nodal dissection. Despite clinical or radiographic “evidence” of lymph node metastasis, 10–20% of these patients were actually metastasis–free upon histologic examination (N0). Conversely, approximately 20%–40% of patients staged clinically as N0 actually had metastatic disease.3 Hence, clinical staging of lymph node status in oral tongue squamous cell carcinoma (SCC) require further investigations for more accuracy.

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Article: Download PDF   DOI : 10.36106/ijsr  

Cite This Article:

Dr Akhlak Hussain, Dr Nida Siddiquee, Role of Extrinsic muscle involvement in tongue cancer: worse or not- A review, INTERNATIONAL JOURNAL OF SCIENTIFIC RESEARCH : Volume-6 | Issue-12 | December-2017


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