Study of Microorganisms Associated with  Hospital Acquired Infection in Intensive  Care Unit and their Antibiotic Resistance  Pattern

Dr Beena Patel; Dr Nilesh Patel; Dr Kalpesh Hansora; Dr Mahesh Choudhary.

Volume : II, Issue : VI, June - 2013

Study of Microorganisms Associated with Hospital Acquired Infection in Intensive Care Unit and their Antibiotic Resistance Pattern

Dr Beena Patel, Dr Nilesh Patel, Dr Kalpesh Hansora, Dr Mahesh Choudhary.

Abstract :

Patients in intensive care unit are about 5 times more likely to acquire nosocomial infection than other ward patients. Present study aimed to study distribution of HAIs in ICUs by anatomical sites, microorganisms associated with HAIs in ICUs and their antibiotic resistance pattern. Study design: The present study was conducted in ICUs of our general hospital during period from November 2008 to November 2010 among 100 randomly selected patients who developed HAIs in ICUs. Results: The most common HAIs in ICUs was LRTI (44.0%) followed by UTI (31.0%), skin, soft tissue and surgical site infection (17.0%) . Most common microorganism associated with HAIs in ICU was P. aeruginosa (31.0%) followed by Klebsiella Spp. (28.0%), E.coli and other enterobacteriaceae (19.0%). Most of the microorganisms associated with HAIs were resistant to commonly used antibiotics, also a higher rate of resistance to higher antibiotics like aztreonam, cefepime, imepenem and amikacin. No resistance was seen to polymyxin B and colistin among gram negative bacilli associated with HAIs. Recommandetions: Every hospital having ICUs must have policies for proper and judicious use of antibiotics and develop protocols to take proper measures to prevent common health care associated infections. Key words: hospital acquired infection, microorganisms, antibiotic, intensive care unit.