Thyroid dysfunction and it’s relation with Type 2 Diabetes Mellitus in Meerut

Sonali Chaturvedi; Suryakant Nagtilak; Pawan Parashar; Amit Rastogi; Akash Gupta

Volume : V, Issue : VII, July - 2016

Thyroid dysfunction and it’s relation with Type 2 Diabetes Mellitus in Meerut

Sonali Chaturvedi, Suryakant Nagtilak, Pawan Parashar, Amit Rastogi, Akash Gupta

Abstract :

Introduction – Diabetes mellitus 2 and thyroid disorders are the two most common endocrinological disorders seen in Indian population. Present study was done to know the prevalence of Thyroid dysfunction in Type 2 Diabetes Mellitus case subjects in and around Meerut city. Materials and methods– In the our study 100 type 2 diabetic subjects and 50 healthy non diabetic subjects were investigated for fasting plasma glucose (FPG), total tri–iodo–thyronine (T3), tetra–iodo–thyronine (T4), thyroid stimulating hormone (TSH), total cholesterol(TC), serum trigyceride(TG), high density lipoprotein(HDL) and glycosylated haemoglobin (HbA1c). Result– Prevalence of thyroid dysfunction is high at 31% in this study population of Type 2 Diabetes Mellitus as compared to 12% in controls. Mean HbA1c in T2DM subjects was 8.31%. Female suffered more from thyroid dysfunction in both case and control group as compared to male. Fasting plasma glucose and Lipid profile was significantly deranged in T2DM subjects as compared to control. In the thyroid profile; T3 in T2DM subjects was significantly decreased as compared to controls. TSH levels were significantly increased in T2DM subjects in comparison to control. Conclusion– The study revealed that there is significant rise of TSH level among diabetic patients.