IJSR International Journal of Scientific Research 2277-8179 Indian Society for Health and Advanced Research ijsr-5-7-007 Original Research Paper Evaluation of platelet indices in patients with dengue infections NeharaHardeva RamDr 1 MeenaShyam LalDr 1 ParmarSahilDr 2 GuptaB. K.Dr. 3 Assistant Professor, Department of General Medicine, Sardar Patel Medical College, Bikaner, Rajasthan, India Third Year Resident, Department of General Medicine, Sardar Patel Medical College, Bikaner, Rajasthan, India Senior Professor, Department of General Medicine, Sardar Patel Medical College, Bikaner, Rajasthan, India 7 2016 5 7 18 21 Abstract

Recently, novel platelet indices such as MPV, PDW, and P-LCR have been investigated as prospective platelet activation markers. The aim of our study was to investigate the platelet indices in dengue patients and to assess the role of it in the severity dengue infection. The platelet parameters of 200 patients were compared with 200 apparent healthy normal individuals. In our study, there was a significantly lower Platelet count and PCT in DHF group as compared to DF group (P<0.0016 and <0.0166 respectively) and significantly higher PDW in DHF group as compared DF group (P<0.0008). High P-LCR, High PDW and low PCT were more sensitive for DHF. In conclusion, low platelet count, low PCT and high PDW may be used as predictor of severity of Dengue infection. Low MPV, low PCT, high P-LCR and high PDW showing considerable sensitivity and specificity for dengue fever. Keywords: Mean platelet volume, Dengue, thrombocytopenia, Platelet distribution width, Bikaner.

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