IJSR International Journal of Scientific Research 2277-8179 Indian Society for Health and Advanced Research ijsr-5-7-014 Original Research Paper Correlation of cord blood malondialdehyde with birth weight and placental weight in newborns MahitaB. DurgaDr. 1 MabenRoshanDr. 2 Post graduate student (MD Paediatrics), Department of Paediatrics, A J Institute of Medical Sciences, Mangalore. Professor (MD Paediatrics), Department of Paediatrics, A J Institute of Medical Sciences, Mangalore. 7 2016 5 7 44 46 Abstract

Background: Oxidative stress injury has been linked with some clinical conditions in newborn. Measuring placental and birth weight along with other features may help in predicting likelihood of oxidative stress injury, babies have suffered. Lipid peroxides are unstable indicators of oxidative stress in cells that decompose to form more complex and reactive compounds such as Malondialdehyde (MDA) bi-product of lipid peroxidation.

Aim: To measure birth weight and placental weight of new born babies as well as determining cord blood malondialdehyde levels (product of oxidant injury).

Methods: Seventytwo term newborns were recruited into the study. Their birth weight and placental weight are recorded and serum cord blood was used for thedetermination of MDA and uric acid. MDA levels were measured using ELISA Kit.

Results: There were positive correlations between placental weight and uric acid and between birth weight and uric acid. There were significant negative correlations between placental weight and MDA.

Conclusion: The weight of the placenta is negatively correlated with cord blood MDA.

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