Introduction- Acute interstitial nephritis is a leading cause of acute kidney injury. Most common etiologies for AIN are medicines such as Antibiotics and Nonsteroidal anti inflammatory drugs. Chinese herb (Aristocholic Acid) is a well known cause of AIN1'2'3. There are no published case reports of Indian indigenous drugs.

Method- We are reporting cases series of three patients.

Result- Three patients presented with Nonoliguric AKI.

First case resolved with short course of steroids, whereas second case resolved spontaneously. The third patient showed partial improvement but developed sepsis and expired.

Consulsion -Indigenous drugs are routinely prescribed and taken, however very few cases have been published as most of the time these are unidentified and unreported. So there is an urgent need to check the safety of these indigenous drugs.