IJSR International Journal of Scientific Research 2277-8179 Indian Society for Health and Advanced Research ijsr-5-11-012 Original Research Paper Misoprostol in the management of missed abortion ThakkarChhaya R.Dr. 1 PatelBabulal S.Dr. 2 3rd year resident, DEPARTMENT OF OBSTETRICS & GYNAECOLOGY, Smt.N.H.L. MEDICAL COLLEGE, AHMEDABAD, GUJARAT. Professor and Head of unit, DEPARTMENT OF OBSTETRICS & GYNAECOLOGY, Smt. N. H. L. MEDICAL COLLEGE, AHMEDABAD, GUJARAT. 11 2006 5 11 36 38 Abstract

Objectives: The aim of study is to evaluate the safety, efficacy and reliability of regimen of vaginal misoprost as a medical method of termination in 1st& 2nd trimester missed abortion.

Method: It is a prospective study carried out in90 women of missed abortion confirmed by transvaginal ultrasound. After fitness and consent of the patients Misoprostol tablet 200 μgm was inserted vaginally every 4 hours of maximum 5 doses. Time for latent period and induction abortion interval was noted and all patients monitored carefully. Surgical evacuation was performed when complete exclusion was not documented on ultrasound after 24 hours of treatment.

Result:

Complete medical evacuation occurs in 54 women (60%)

Mean induction abortion interval was 13.37 hours

Conclusion:

Misoprost is a safe reasonably effective medical method in including complete evacuation in missed abortion, when this doesn't occurs it almost always adequate cervical dilatation for surgery.

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