IJSR International Journal of Scientific Research 2277-8179 Indian Society for Health and Advanced Research ijsr-5-9-018 Original Research Paper A study of anti retro viral therapy for HIV infection in pediatric age group in Rajasthan UpadhyayaAlokDr. 1 * BilwalRakeshDr. 2 Assistant Professor, J.k. Lon Hospital & S.M.S. Medical college, jaipur, Rajasthan. Senior Resident, J.k. Lon Hospital & S.M.S. Medical college, jaipur, Rajasthan *Assistant Professor, J.k. Lon Hospital & S.M.S. Medical college, jaipur, Rajasthan 9 2016 5 9 48 50 Abstract

Introduction: More than 1,000 children are newly infected with HIV every day, and of these more than half will die as a result of AIDS because of a lack of access to HIV treatment.

Material & Methods: In this study (Dr. S.N. medical college, jodhpur) 280 HIV positive children (1-15 year age) were enrolled. 5 Ml venous blood was drawn by patients, then serum was separated for CD4 count and HIV by ELISA.

Result: After anti retroviral therapy there was significant decrease in number of cases with immunosuppression.

Conclusion: Transmission of HIV reduced by antiretroviral therapy during antenatal period.

 Keywords HIV AIDS ART CD4+count References WeissRA(May1993). “How does HIV cause AIDS?”. Science260 (5112): 1273–9. doi:10.1126/science.8493571. PMID 8493571. CDC – HIV/AIDS – Resources – HIV Prevention in the United States at a Critical Crossroads”. Cdc.gov. http://www. cdc.gov/hiv/resources/reports/hiv_prev_us.htm. Retrieved 2010-07-28. “HIV and AIDS among Gay and Bisexual Men” (PDF). http://www.cdc.gov/nchhstp/newsroom/docs/Fast Facts-MSM-FINAL508COMP.pdf. Retrieved 2010-07-28. Joint United Nations Programme on HIV/AIDS. “AIDS epidemic update, 2005” (PDF). http://www.unaids.org/epi/2005/doc /EPIupdate2005 _pdf_en/epi-update2005_en.pdf. Retrieved 2006-02-28. PalellaF. J. JrDelaneyK. M.MoormanA. C.LovelessM. O.FuhrerJ.SattenG. A.Aschman D. J.HolmbergS. D. (1998). “Declining morbidity and mortality among patients with advanced human immunodeficiency virus infection. HIV Outpatient Study Investigators”. N. Engl. J. Med338 (13): 853–860. doi:10.1056/NEJM199803263381301. PMID 9516219. LawnSD (2004). “AIDS in Africa: the impact of coinfections on the pathogenesis of HIV-1 infection”. J. Infect. Dis.48 (1): 1–12. doi:10.1016/j.jinf.2003.09.001. PMID 14667787. BuchbinderSPKatzMHHessolNAO'MalleyPMHolmbergSD. (1994). “Long-term HIV-1 infection without immunologic progression”. AIDS8 (8): 1123–8. doi:10.1097/00002030-199408000-00014. PMID 7986410. “Time from HIV-1 seroconversion to AIDS and death before widespread use of highly active antiretroviral therapy: a collaborative re-analysis. Collaborative Group on AIDS Incubation and HIV Survival including the CASCADE EU Concerted Action. Concerted Action on Sero Conversion to AIDS and Death in Europe”. Lancet355 (9210): 1131–7. April2000.doi:10.1016/S0140-6736(00)02061-4. PMID 10791375. SchneiderMFGangeSJWilliamsCMAnastosKGreenblattRMKingsleyLDetelsRMunozA (2005). “Patterns of the hazard of death after AIDS through the evolution of antiretroviral therapy: 1984–2004”. AIDS19 (17): 2009–18. doi:10.1097/01.aids.0000189864.90053.22. PMID 16260908. UNAIDS (2010) ‘UNAIDS report on the global AIDS epidemic’. UNAIDS (2010) ‘UNAIDS report on the global AIDS epidemic’. GarciaJVMillerAD (April1991). “Serine phosphorylation-independent downregulation of cell-surface CD4 by nef”. Nature350 (6318): 508–11. doi:10.1038/350508a0. PMID 2014052. PryceCPierreRBSteel-DuncanJEvan-GilbertTPalmerPMooreJRodrguezBChristieCDC ,Safety of antiretroviral drug therapy in Jamaican children with HIV/AIDS WestIndian med. J. vol.57 no.3Mona June2008. Human Rights Watch (2006,August) ‘Life Doesn't Wait - Romania's Failure to Protect and Support Children and Youth Living with HIV’.