Pseudoexfoliation (PXF) is a senile condition, more common in females, familial and seems to be genetically inherited disease. A high risk of developing pseudoexfoliation   syndrome and pseudoexfoliation glaucoma is confirmed by mutations in LOXL1 gene at locus 15q22, coding for elastic fibre components of the extracellular matrix. A grey–white fibrillary extracellular material composed of a protein core surrounded by glycosaminoglycans is produced by abnormal basement membranes of ageing epithelial cells in the trabeculum, equatorial lens capsule, iris and ciliary body. The material is then deposited on the anterior lens capsule, zonules, ciliary body, iris trabeculum, anterior vitreous face and conjunctiva.