Background: Dentinal hypersensitivity (DH) is a painful response of a tooth to irritants such as toothbrushing, sweet or sour foods, and thermal changes. It is a cumbersome condition both for the patient and the dental care providers as well.

Aim:  to compare the clinical efficacy of four different commercially available dentifrices in the management of dentinal hypersensitivity.

Materials & Methods: A total of 160 patients clinically diagnosed with dentinal hypersensitivity (93 males and 67 females) participated in this study. The participants were randomly divided into four groups: Group 1 – toothpaste containing 5% potassium nitrate; Group 2 – toothpaste containing 5% fluoro calcium phosphosilicate ; Group 3 – toothpaste containing 10% strontium chloride; and Group 4 – a herbal formulation. The patients’ DH scores for tactile, thermal, and evaporative stimuli were recorded on a visual analog scale at baseline, 2 weeks, 1 month, and 2 months.

Results: Symptoms of dentinal hypersensitivity were reduced in all four groups. However, group 2 showed a better clinical response.

Conclusions: The dentifrice containing fluoro calcium phosphosilicate is more efficacious in managing dentinal hypersensitivity.