Since Buschke and Lowenstein first described the giant condyloma in 1925( which subsequently was named as Buschke – Lowenstein tumour),there have been scatterd reports over the past 90 years describing presentation and different avenues of the treatment for patients with this condition. Anogenital warts (condyloma acuminatum or veneral warts) are a common sexually transmitted disease among females and males . The causal role of Human papiloma virus(HPV) in anogenital wart formation has been firmly established biologically and epidemiologically. The mode of treatment range from application of podophyllin to surgical excision . We present a case of 32 years old married female with a presentation of giant condyloma acuminata whose surgically excised specimen was received in our laboratory. ‘