The objective of research was to study the outcome of acute kidney injury (In tropical acute febrile illness) with mortality and dialysis requirement. The study was conducted at our a tertiary care institute in Maharashtra between October 2014 to November 2016. We studied  application of RIFLE criteria for AKI classification, outcome  of AKI with RRT  requirement and mortality. It was a descriptive longitudinal study. We recruited 140 confirmed cases of tropical acute febrile illnesses (TAFI) hospitalized in medicine wards, medical ICU and kidney unit. Out of total 39 patient of AKI in present study maximum 16(11.43%) belong to failure class, 13(9.29%) belong to risk class and 10(7.14%) belong to injury class according to RIFLE staging. Mortality of patient in AKI group10 (25.60%)  was significantly higher than non AKI group6 (5.90%). Hence, AKI is a significant risk factor for mortality.