IJSR International Journal of Scientific Research 2277 - 8179 Indian Society for Health and Advanced Research ijsr-6-3-10273 Original Research Paper A STUDY OF CLINICAL PROFILE AND OUTCOME IN ACUTE VIRAL HEPATITIS E IN RAIPUR CG Sunil Kumar Mudgal Dr. Dr Brajendra Kumar Dr. March 2017 6 3 01 02 ABSTRACT

 Acute viral hepatitisE (HEV) is generally mild and self–limiting and resolves within six weeks, with no chronic sequelae. Pregnant women are at increased risk with the risk increasing as the pregnancy progresses near term.We performed a prospective study of 100 patients who presented to Dept. of Pediatrics, RIMS,Raipur,CG,India–492001, with jaundice (IgM anti–HEV positive) during 2015–2016 and data were analyzed for the clinical profile and outcome of HEV.The most common age group affected was 05–10 years with overall M:F ratio of 3.4:1. Most common presenting symptom was jaundice (100%) followed by nausea/vomiting (87%). On presentation, serum bilirubin level was elevated in 89% patients with SGPT raised in 86%. PT was prolonged in 39% patients. Anemia (Hb < 7) was seen in 17% while 9% of patients had renal involvement. Hepatic encephalopathy was seen in 15%.  Overall mortality was 7%.We found that majority of cases were cured with supportive treatment.