IJSR International Journal of Scientific Research 2277 - 8179 Indian Society for Health and Advanced Research ijsr-6-3-10308 Original Research Paper HISTOPATHOLOGICAL ANALYSIS OF HODGKIN’S LYMPHOMAS WITH SPECIAL REFERENCE TO EPSTEIN –BARR VIRUS Dr. March 2017 6 3 01 02 ABSTRACT

 Abstract:            Introduction Epstein–Barr Virus(EBV) is a herpes virus and EBV positive tumour cells express latent membrane protein–1(LMP–1), a protein encoded by EBV genome that has transforming activity.EBV virus infects B–lymphocytes, which will emerge as lymphomas Aim : To demonstrate EBV antigen in tissue sections of Hodgkin’s  lymphomas (HL) by immunohistochemistry (IHC)  and to   investigate the relationship between EBV associated HL in view of age, sex, site and subtype   Material And Methods:  39 cases of Hodgkin’s lymphomas were taken  for histopathological examination & IHC marker LMP–1 study. Conclusion:. LMP–1 expression is more common in males,mixed cellularity subtype, age > 45 years and in cervical nodes.