Gastrointestinal stromal tumors (GISTs) are neoplasms of the gastrointestinal tract. Despite their less aggressive pathologic nature, GISTs can metastasize and recur after a long remission period. Metastatic GIST may produce serious morbidity and mortality. It leads to complex management issues for the treating physician. We hereby report the case of a patient who presented with a large Gastric GIST with a synchronous liver metastasis that was successfully treated with excision of Gastric GIST with hepatic metastatectomy. We also highlight the literature on Gastric GIST with liver metastasis, treatment options and prognosis of the disease.