Enteric fever is a major multi–systemic bacterial infection which remains an important public problem in developing nations. More recently paratyphoid fever has become the frequent cause of enteric fever in some areas. Fluoroquinolones and third–generation cephalosporins are currently the drugs of choice for the treatment of paratyphoid fever, although decreased susceptibility to these antimicrobials have also been reported in some areas. In this retrospective study, the records of culture positive paratyphoid fever cases during the period of march 2016 to august 2016 were obtained. Antibiotic sensitivity patterns were assessed based on culture and sensitivity, all the patients were sensitive to Ampicillin and Chloramphenicol. All the patients were resistant to Quinolones (ciprofloxacin) and Aminoglycosides. Sensitivity to Ceftriaxone is seen in 16/18 (88.8%). The existence of multidrug – resistant bacteria is a serious and growing problem. This situation has been further complicated by the emergence of quinolone resistant strains.