Different types of dressings such ashydrocolloid, alginates, paraffin gauzeand hydro–cellularhave been tested during the past few years in an attempt to reduce pain. Our study shows significant pain reduction when using platelet rich plasma (PRP). The effect was virtually long lasting and without the need for repeated application. Some patients who had previously healed skin graft donor site wounds noted the difference in treatment and found the recovery relatively pain free.Recently, we observed an increase in patient satisfaction following PRP application to split–thickness skin graft (STSG) donor sites. We assessed all patients included in our criteria at theuniversity–based hospital service who underwent STSGsfrom 2014–2016.Based on these criteria, donor site pain was measured by pain analogue scale.