Westergren method is the reference method to measure Erythrocyte Sedimentation Rate (ESR) by the International Council for Standardization in Haematology. However, a closed semi automated method, VES Matic easy (DIESSE ,Italy), has been introduced as a new ESR measurement instrument. In this article, we compared the two methods (Westergren and VESMatic easy ). The results obtained using VES Matic easy showed a good correlation with those obtained using the Westergren method.  Supporting the hypothesis that VES Matic easy offers a fast and safe ESR determination, ensuring precision and a very good correlation with the reference method.