Background: Supraspinatus tendonitis is found to be one of the most common causes for the Shoulder pain. Deep friction massage (DFM) can be applied to treat musculoskeletal pain, inflammation and adhesions. Even though, US is used to stimulate tissue healing and repair, US therapy alone is less effective in treating soft tissue disorders. So the objective of the present study is to compare the combined therapy of US and DFM versus US therapy alone in the management of supraspinatus tendonitis. Materials and Methods: Seventeen male patients diagnosed with supraspinatus tendonitis were randomly distributed into two different groups. Group (A) treated by therapeutic US and DFM and group (B) treated by therapeutic US alone. The outcome tools used to evaluate the effect were the Visual Analogue Scale (VAS) and active abduction range of motion (AROM– ABD) in shoulder joint. Results: The results shows that, at the end of the treatment, the VAS as well as shoulder abduction ROM showed significant changes in the group A than in the group B. Conclusion: The combination of US treatment and DFM were significantly more effective than the US alone in management of supraspinatus tendonitis.