Objective: To determine the consumption of alcohol as a factor in the decontrol of glucose in patients with diabetes mellitus. Methods: An observational, analytical, cross–sectional, prospective study was carried out in patients attending the "Luis Gil Pérez" expanded health center in Centro, Tabasco, Mexico, in May 2016, using non–probabilistic sampling for convenience, (P> 0.05). Results: 23.07% of the patients were normoglycemic, four positive cases were found in glycemic control and alcohol intake without significant relation (p> 0.05). Alcohol intake and diabetes mellitus remain a major public health issue.