IJSR International Journal of Scientific Research 2277 - 8179 Indian Society for Health and Advanced Research ijsr-6-3-10452 Original Research Paper Use of Magnetic resonance imaging and Diffusion tensor weighted imaging in intractable epilepsy R.M. Bhoopathy Dr. S.S.Vignesh Dr. March 2017 6 3 01 02 ABSTRACT

 506 patients with intractable epilepsy were assessed using magnetic resonance imaging (MRI) and Diffusion Tensor Weighted Imaging (DTWI) to identify structural lesions. A significant proportion of patients in MRI presented with Malformation of cortical development (MCD), Mesial temporal sclerosis (MTS) and non specific lesions.  DTWI could identify various white matter abnormalities in same side or in bilateral hemispheres.  Though the MRI revealed structural abnormalities at one hemisphere, the DTWI revealed white matter abnormalities in same or both hemispheres. In addition patients suffering from complex partial seizure and MRI (without any abnormalities) revealed white matter abnormalities in various region of interest studied bilaterally or unilaterally. Thus the epileptic network in intractable epilepsy is extensive and stresses the need to study further.